CBD: Question The Claims About It

Highlights

•Cannabidiol (CBD) products have varying amounts of CBD, from none to much more than advertised.
•CBD products may contain other chemicals than CBD, some of which may be harmful.
•Sixteen RCTs for pain used pharmaceutical CBD in oral, buccal/sublingual, and topical forms.
•Fifteen of the 16 RCTs were negative: no greater pain-relieving effect for CBD than for placebo.
•Meta-analyses link CBD to increased rates of serious adverse events and hepatotoxicity.

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Cannabidiol (CBD) Products for Pain: Ineffective, Expensive, and With Potential Harms