Let The Mystery Be

The main problem with promoters of religion, alternatives to medicine and all other pseudoscience is that they move past the knowledge provided by science.  This is called The Argument from Ignorance or if it is from the religious, The God of the Gaps Argument.  Why do this?  This article explains the situation quite succinctly and clearly. Wouldn't you think that if one God was real, one religion's claims would be accepted by science and there would be no gaps?

Why not just stay within what we really know and just "Let the Mystery Be?"